Episode 1 : Erica Noughton
As Sean reluctantly celebrates his 40th birthday, Christian urges him to take advantage of some of the youth-preserving treatments available at the clinic.
Episode 2 : Christian Troy
Sean suffers uncontrollable spasms in his hands. After he nicks a patient's major neck artery during a routine cyst lancing, Sean stops performing surgeries.
Episode 3 : Manya Mabika
Christian and Sean agree to rehabilitate a stalwart, optimistic Somali woman, Manya Mabika (Aisha Tyler - "Friends," "Talk Soup," pilot "My Life, Incorporated"), who was genitally mutilated as a girl in her home country.
Episode 4 : Mrs. Grubman
Sean and Julia are shocked to discover that 8-year-old Annie (recurring guest star Kelsey Lynn Batelaan) is entering puberty already.
Episode 5 : Joel Gideon
While driving home, Sean is broadsided by another car and rushed to the hospital. He was saved from major injury by his vehicle's safety devices, but his view of life has changed.
Episode 12 : Julia McNamara
After taking too many painkillers and drinking alcohol, Julia has fallen through a glass door, severely damaging her face.
Episode 14 : Trudy Nye
Sean and Christian reluctantly accept the case of Trudy Nye (Lisa Waltz), who wants her nose fixed.
Episode 15 : Sean McNamara
Sean has been operating pro bono on victims of The Carver, a serial rapist who chooses good-looking people and carves their faces as a message to society about beauty and conformity.
Episode 16 : Joan Rivers
Celebrity Joan Rivers (herself), who is famous for having undergone many cosmetic surgeries, consults with the doctors. However, what Joan requests astonishes even Sean and Christian.